Implantation failure and recurrent miscarriages account for up to 20% of failed IVF treatments. At Fertility Madrid, we are at the forefront of assisted reproduction treatments, combining experience and technology to help our patients fulfil their dream of becoming mothers.

Our laboratory has long embraced the use of cytokines as part of an advanced approach to In Vitro Fertilisation (IVF) treatments. This treatment is designed to regulate embryonic development, improve intercellular communication between the embryo and the endometrium, thereby increasing the rate of implantation and evolving pregnancy.


What is Embryo Implantatión in Assisted Reproduction?

Embryo implantation is a key moment in fertility treatments, as the embryo must attach to the endometrium to continue its development and achieve a successful pregnancy. However, in some cases, embryos have difficulty implanting, especially in women with a history of implantation failure or recurrent miscarriages.

To address these challenges, improving the environment in which embryos are cultured prior to transfer can make all the difference. That is why at Fertility Madrid we have adopted an innovative culture medium that incorporates cytokines– essential molecules that regulate communication between embryo and reproductive tissues.


Innovation in IVF:Thee GM-CSF Culture Medium

SAGE 1-Step GM-CSF, which we use regularly in our procedures, includes Granulocyte and Macrophage Colony Stimulating Factor (GM-CSF). This cytokine acts as a “specialised nutrient” which aids better recovery after devitrification, protecting against apoptosis and cellular stress. This will benefit both embryo implantation as well as pregnancy maintenance.

Benefits of GM-CSF culture medium:

  • Reduction in the number of attempts needed to achieve pregnancy.
  • Regulates embryonic development.
  • Protects against apoptosis and cellular stress.
  • Increases implantation rates in IVF treatments.
  • Increases chances of success in women with a history of implantation failure or recurrent miscarriage.
  • Improved immune response for a safer pregnancy.

Results Supported by Scientific Studies

Recent studies have shown that this embryo culture medium can make a big difference:

  • Pregnancy rates in women with implantation failure: improvement up to 40% compared to 28% with traditional methods.
  • Overall improvement in embryo quality, with embryos showing less apoptosis and cellular stress, thus improving the results in the transfer of cryopreserved embryos.

These figures support the positive impact of this innovative approach to IVF, especially in difficult cases.


Fertiity Madrid: Committed to Innovation

At Fertility Madrid, we are continuously working to offer our patients the latest in assisted reproduction treatments. Incorporating technologies such as GM-CSF culture medium allows us to improve success rates in IVF treatments, increasing the chances of pregnancy from the first attempt and reducing the emotional stress associated with previous failures.

If you are interested in learning more about our innovative techniques and how we can help you, please do not hesitate to contact us or request your first free consultation. We are here to be with you every step of the way on the road to motherhood.


Would you like to speak with our psychologist or receive additional support during this process?

Schedule a consultation with us at Fertility Madrid and discover how we can help you navigate this journey with strength and hope.

Do you have any questions or need more information?

At Fertility Madrid we are specialists in treatments such as ovodonation, in vitro fertilisation and artificial insemination, among others.

Do not hesitate to contact our professionals in our fertility clinic and they will answer all your questions without obligation.

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