The biopsy is usually performed on the fifth day after starting progesterone supplementation in a stimulated cycle.
Other laboratory methods
Complementary tests to personalize your fertility treatment
At Fertility Madrid, we offer additional laboratory methods that help optimize the results of assisted reproduction treatments. Among them are the endometrial receptivity test (ERA) and GERT technology, which allow us to evaluate the endometrium and determine the ideal timing for embryo transfer. These tests provide a more precise and personalized approach, especially in cases of previous implantation failures.
ERA (endometrial receptivity analysis) and GERT (GENNET endometrium receptivity test)
The condition of the endometrium (uterine lining) is crucial for an embryo to implant successfully and for pregnancy to begin.
Unlike traditional ultrasounds, which only assess endometrial thickness and structure, endometrial receptivity tests provide a deeper molecular and genetic view of the tissue.
Unlike traditional ultrasounds, which only assess endometrial thickness and structure, endometrial receptivity tests provide a deeper molecular and genetic view of the tissue.
The ERA (endometrial receptivity array) is a specialised genetic test that evaluates endometrial receptivity to identify the most suitable time for embryo transfer.
We also offer GERT (GENNET endometrium receptivity test), an equally advanced alternative using proprietary technology.
We also offer GERT (GENNET endometrium receptivity test), an equally advanced alternative using proprietary technology.
Recommended indications:
- After two or more failed embryo transfers
- When other studies such as PGT-A, PGT-M or PGT-SR, blood tests and ultrasounds have not identified the cause of implantation failure
How does the endometrial receptivity test work?
Biopsy procedure:
A small sample of the endometrium is taken during a specific and carefully synchronised phase of the menstrual cycle.
This procedure is carried out with a thin plastic cannula, gently introduced through the cervix, without the need for anaesthesia.
Optimal timing:
Results:
The results are available within two weeks and make it possible to determine with precision the optimal implantation window, that is, the best moment to transfer the embryo to the uterus.
For more information about our latest laboratory methods, we invite you to check our price list or contact us directly.
Our team of coordinators will be happy to assist you, answer your questions, and explain in detail each of the techniques we use to help you fulfil your wish of becoming a mother or father.
Frequently asked questions about other laboratory methods
What are the ERA and GERT endometrial receptivity tests?
They are advanced genetic tests that analyse the molecular state of the endometrium to determine the most suitable time for embryo transfer in an in vitro fertilisation cycle.
In which cases is an endometrial receptivity test recommended?
It is usually indicated after several failed embryo transfer attempts, when pregnancy has not been achieved despite using good-quality embryos and other studies (ultrasounds, hormonal analyses, or PGT) have not shown abnormalities.
What is the difference between ERA and GERT?
Both tests have the same goal: to identify the endometrium’s implantation window. ERA is based on a genetic microarray, while GERT uses proprietary technology developed by GENNET. Your specialist will recommend which is most suitable for your case.
How is the endometrial receptivity test performed?
The procedure consists of an endometrial biopsy. Using a thin, flexible cannula, a small sample of uterine tissue is taken at a specific moment of the menstrual cycle. It does not require anaesthesia and usually causes only mild discomfort.
Does the endometrial receptivity test hurt?
Generally no. It may cause a sensation similar to mild menstrual pain, but it does not require sedation and the patient can resume her activities the same day.
What information do ERA or GERT provide?
They indicate whether the endometrium is receptive at the time the sample is taken. With this information, the exact day of embryo transfer can be adjusted to increase the chances of implantation and pregnancy.
Does the endometrial receptivity test increase IVF success rates?
Yes, in patients with repeated implantation failures it can significantly improve the chances of pregnancy, as it makes it possible to personalise the timing of the transfer.